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Is Cbd for Dogs harmful? This is a quote form the America Kennel Club.
Is It Harmful?
Is cbd for dogs harmful? Unlike THC, which can cause toxicity and even death in dogs when given at prescribed human dosages, the worst CBD has been documented to do is cause diarrhea and changes in some liver enzyme values after several weeks. The main concern with CBD is that it inhibits a chemical in the body called cytochrome P450 that is responsible for metabolizing most drugs. If a drug’s efficacy depends on its metabolized product, CBD could render it less effective. If a drug’s safety depends on it being cleared from the body within a certain time frame, CBD could cause it to build up to toxic levels. Never give your dog CBD without your veterinarian’s knowledge if your dog is taking other drugs.
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Does It Work?
Research with dogs is still scarce, but there’s a huge body of research (about 23,000 published papers!) looking at CBD’s effect on laboratory animals and humans, with encouraging results for pain, especially arthritic pain, itchiness, anxiety, and cancer, all of which have at least one canine study as well. The results in dogs? It depends.
Arthritis: Several studies have looked at CBD’s effectiveness against arthritic pain, all with positive results. A Cornell University College of Veterinary Medicine study found dogs given CBD at a rate of 4.4 mg per pound twice daily for a month showed significant improvement in pain relief and quality of life. Lead investigator Joe Wakshlag, DVM, Ph.D., DACVN, said that some dogs were initially so decrepit that their owners considered euthanasia, but that after just days on CBD they were trotting around and even climbing stairs. A Baylor University study found similar improvement, adding that CBD worked better when delivered in a liposomal formulation.
Itchiness: Two recent double-blind, placebo-controlled dog studies report CBD significantly reduces itchiness. An Australian study conducted by the company CannPal found their CBD product reduced itchiness, inflammation, and skin lesions by 51 percent after eight weeks of treatment. An American study conducted by the company ElleVet found their product, which combines CBD with another cannabinoid, CBDA, significantly reduced owners’ reports of itchiness.
Cancer: Cannabinoids are reported to induce cancer-cell death and prevent metastasis. In a Cornell University study of CBD, dogs, and cancer, researchers found CBD along with a standard chemotherapy drug reduced cancer-cell proliferation in vitro more than the chemotherapy drug alone. Anecdotal reports from veterinarians have claimed CBD shrunk cancer cells or put dogs into remission.
Behavior: Anxiety, and especially noise reactivity, is a major reason dog owners seek help using CBD. But despite anecdotal reports of its effectiveness, no controlled study so far has shown it to be particularly effective. A study from the University of Western Australia may show promise for aggressive behavior. Shelter dogs with aggressive tendencies exhibited less aggression toward humans when tested after 15 days of CBD administration. In a study from the University of Kentucky, physiological measurements of anxiety in response to noise were not significantly different for CBD versus placebo, and were worse compared to trazodone (a drug commonly prescribed for anxiety). Note, however, that in this study the CBD was administered four to six hours before testing, which may have been too long a waiting period.
Seizures: Lots of anecdotal reports hail CBD’s success combatting seizures in dogs, but the single controlled study delivered moderate results. In this Colorado State University study, dogs given CBD for 12 weeks had 33 percent fewer seizures than those given a placebo, but it didn’t work for every dog. These researchers are now working on a larger trial using higher CBD doses. Note that THC has been reported to cause seizures, so it should never be included in any CBD product for seizure control. In addition, CBD’s effect on cytochrome P450 could interfere with prescribed anti-seizure drugs, so never use it without your veterinarian’s consent.
Other: There’s also evidence from laboratory animals that CBD is effective in promoting bone healing, fighting infection, treating inflammatory bowel disease, slowing degenerative myelopathy, quelling nausea, and relieving pain, but these have yet to be specifically examined in dogs.
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It looks like the world’s beginning to take notice.
With each passing day, it seems the stigmatized aura surrounding CBD continues to wane.
Cbd receptors in the body for people in {canadacities}
Which is great news for us!
If you’ve been using CBD for any length of time, you know the stigma attached to it is still there.
But reports suggest it may soon become a household ingredient in many of our favourite foods, drinks, products we use day-to-day.
In fact, a recent article in Forbes points to its explosive growth with each coming year, stating, “CBD sales in the U.S. hit $4.6 billionin 2020, a massive number just two years after hemp-derived cannabinoids were federally legalized. This growth is only expected to accelerate, with two notable forecasts projecting a U.S. market of $15 billion to more than $20 billion by 2025 and 2024, respectively.”
In any case, while the research continues, it looks like all signs are pointing up.
This means there’s never been a better time to discover the wonderful benefits CBD has to offer.
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How much and what size of Cbd Oil does a person need for them to start to see resluts?
The smaller the mg the less effective it may be. The larger mg and bottle size work better and last longer.
If you try to cheap out, you will not get the results that might have been wanting, like more energy, sleeping better, pain relief, inflammation reduction.
The simple rule of thumb is “The More The Better” and “Bigger is Better” Right?
However, if you do decide to try CBD, it is also important to note that there is no universally agreed-upon dose.
Here are some studies that have been done and their thoughts.
Some dosages that have been used in research studies for different conditions include:
Anxiety: 300 to 600 mg7
Bowel disease: 10 mg per day8
Cancer-related pain: 50 to 600 mg per day9
Parkinson’s disease: 75 to 300 mg per day10
Poor sleep: 25 mg per day2
Psychosis: 600 mg per day8
A one-size-fits-all dosage for CBD doesn’t exist. Even the FDA doesn’t provide a Recommended Daily Intake (RDI) for CBD.
So make sure you use common sense and listen to what your body is telling you.
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If your doctor doesn’t give you a recommendation, it’s best to start with a smaller dosage and gradually increase it.
This could mean starting with 20 to 40 mg a day. After a week, increase this amount by 5 mg.
Continue this until you feel that it’s effectively treating your symptoms.
Again, please listen to your body, it knows what it needs and how much.
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